Endometriosis
Beyond the pain.
Important: R1SE services are complementary wellness support, not medical treatment. Always consult your healthcare provider before starting any new programme, especially if you are under active medical care.
Endometriosis affects 1 in 10 women in the UK and the average diagnosis takes over 7 years. At R1SE Sheffield, we cannot diagnose or treat endo - but we can offer evidence-informed therapies that help manage the chronic pain, fatigue, and inflammation that define this condition.
Endometriosis is no longer understood as a simple 'lost tissue in the wrong place' problem. Modern research frames it as a chronic, systemic inflammatory disease driven by oestrogen-dependent lesions, elevated prostaglandins, peripheral and central pain sensitisation, and often a dysregulated autonomic nervous system that locks the pelvic floor into chronic guarding. This is why surgery and hormonal suppression alone rarely resolve pain entirely - and why NICE guideline NG73 explicitly recommends multi-modal management including pain-management services, pelvic-floor physiotherapy, psychological support and lifestyle interventions. At R1SE we cannot replace your endo team, but we can layer in the lifestyle side: heat (for prostaglandin-driven cramp), photobiomodulation (for tissue inflammation), gentle pelvic-focused yoga (for fascial and pelvic-floor tone), HBOT (for immune modulation), and pneumatic compression (for pelvic circulation and fluid balance).
Your Multi-Therapy Plan
How R1SE Can Help
The Science
Evidence-based insights supporting our approach.
A 2017 RCT (Gonçalves et al., Journal of Alternative and Complementary Medicine) showed 8 weeks of twice-weekly yoga significantly reduced chronic pelvic pain intensity and improved quality of life in women with endometriosis - with effects sustained after intervention.
Endometriosis involves both peripheral sensitisation (local inflammation) and central sensitisation (a rewired spinal-cord and brain pain response). This explains why pain persists even after surgical removal of lesions - and why multi-modal approaches (body-work, nervous-system regulation) matter (As-Sanie et al., 2016, Pain).
NICE guideline NG73 (2017, updated) explicitly recommends a multi-modal approach to endometriosis management, including pain-management services, pelvic-floor physiotherapy, psychological support, and lifestyle interventions alongside medical and surgical care.
Photobiomodulation has demonstrated anti-inflammatory and pro-regenerative effects on endometrial and peritoneal tissue in pre-clinical studies (de Sousa et al., 2020, Lasers in Medical Science). Human trials for chronic pelvic pain syndromes are underway.
Regular moderate exercise has been associated with 76% lower odds of severe endometriosis pain in population studies (Bonocher et al., 2014, Human Reproduction) - likely via reduced systemic oestrogen, reduced inflammation, and improved endogenous pain modulation.
Pelvic-floor muscle dysfunction (overactivity, trigger points, asymmetry) is present in the vast majority of women with endometriosis and is itself a significant pain generator (Aredo et al., 2017). Yoga practices that emphasise diaphragmatic breathing and pelvic release target this directly.
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